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Genetic Manipulation of The Cardiac Mitochondrial Phosphate Carrier does not affect Permeability Transition

The Mitochondrial Permeability Transition (MPT) pore is a voltage-sensitive unselective channel known to instigate necrotic cell death during cardiac disease. Recent models suggest that the isomerase cyclophilin D (CypD) regulates the MPT pore by binding to either the F(0)F(1)-ATP synthase lateral s...

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Autores principales: Gutiérrez-Aguilar, Manuel, Douglas, Diana L., Gibson, Anne K., Domeier, Timothy L., Molkentin, Jeffery D., Baines, Christopher P.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080311/
https://ncbi.nlm.nih.gov/pubmed/24768964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.04.008
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