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The roles of phosphate and the phosphate carrier in the mitochondrial permeability transition pore

Phosphate activation of the mitochondrial permeability transition pore (MPTP) opening is well-documented and could involve the phosphate carrier (PiC) that we have proposed is the pore's cyclophilin-D binding component. However, others have reported that following CyP-D ablation Pi inhibits MPT...

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Hlavní autoři: Varanyuwatana, Pinadda, Halestrap, Andrew P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Science 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281194/
https://ncbi.nlm.nih.gov/pubmed/21586347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2011.04.006
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