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Phosphate Is Essential for Inhibition of the Mitochondrial Permeability Transition Pore by Cyclosporin A and by Cyclophilin D Ablation

Energized mouse liver mitochondria displayed the same calcium retention capacity (a sensitive measure of the propensity of the permeability transition pore (PTP) to open) irrespective of whether phosphate, arsenate, or vanadate was the permeating anion. Unexpectedly, however, phosphate was specifica...

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Detalhes bibliográficos
Main Authors: Basso, Emy, Petronilli, Valeria, Forte, Michael A., Bernardi, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546556/
https://ncbi.nlm.nih.gov/pubmed/18684715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C800132200
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