Phosphate Is Essential for Inhibition of the Mitochondrial Permeability Transition Pore by Cyclosporin A and by Cyclophilin D Ablation

Energized mouse liver mitochondria displayed the same calcium retention capacity (a sensitive measure of the propensity of the permeability transition pore (PTP) to open) irrespective of whether phosphate, arsenate, or vanadate was the permeating anion. Unexpectedly, however, phosphate was specifica...

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Bibliographic Details
Main Authors: Basso, Emy, Petronilli, Valeria, Forte, Michael A., Bernardi, Paolo
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546556/
https://ncbi.nlm.nih.gov/pubmed/18684715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C800132200
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