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Enhancement of anxiety, facilitation of avoidance behavior, and occurrence of adult-onset obesity in mice lacking mitochondrial cyclophilin D

In this report, we have assessed the behavioral responses of mice missing the Ppif gene (CyPD-KO), encoding mitochondrial cyclophilin D (CyPD). Mitochondrial CyPD is a key modulator of the mitochondrial permeability transition which is involved in the regulation of calcium- and oxidative damage-indu...

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Autori principali: LUVISETTO, Siro, BASSO, Emy, PETRONILLI, Valeria, BERNARDI, Paolo, FORTE, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057224/
https://ncbi.nlm.nih.gov/pubmed/18621101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2008.06.030
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