Low-dose paclitaxel ameliorates fibrosis in the remnant kidney model by down-regulating miR-192

Transforming growth factor (TGF)-β has been shown to play a central role in the development of tubulointerstitial fibrosis, which can be corrected via treatment with paclitaxel. The biology of microRNA (miR) can be modulated by paclitaxel. We hypothesized that paclitaxel may attenuate renal fibrosis...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sun, Lin, Zhang, Dongshan, Liu, Fuyou, Xiang, Xudong, Ling, Guanghui, Xiao, Li, Liu, Yinghong, Zhu, Xuejing, Zhan, Ming, Yang, Yeyi, Kondeti, Vinay K, Kanwar, Yashpal S
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Ltd. 2011
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258545/
https://ncbi.nlm.nih.gov/pubmed/21984124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2961
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