Probucol ameliorates renal injury in diabetic nephropathy by inhibiting the expression of the redox enzyme p66Shc

AIMS: Probucol is an anti-hyperlipidemic agent and a potent antioxidant drug that can delay progression of diabetic nephropathy (DN) and reverses renal oxidative stress in diabetic animal models; however, the mechanisms underlying these effects remain unclear. p66Shc is a newly recognized mediator o...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Yang, Shikun, Zhao, Li, Han, Yachun, Liu, Yu, Chen, Chao, Zhan, Ming, Xiong, Xiaofen, Zhu, Xuejing, Xiao, Li, Hu, Chun, Liu, Fuyou, Zhou, Zhiguang, Kanwar, Yashpal S., Sun, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514499/
https://ncbi.nlm.nih.gov/pubmed/28728079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.07.002
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