Rap1 Ameliorates Renal Tubular Injury in Diabetic Nephropathy

Rap1b ameliorates high glucose (HG)-induced mitochondrial dysfunction in tubular cells. However, its role and precise mechanism in diabetic nephropathy (DN) in vivo remain unclear. We hypothesize that Rap1 plays a protective role in tubular damage of DN by modulating primarily the mitochondria-deriv...

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Detalhes bibliográficos
Main Authors: Xiao, Li, Zhu, Xuejing, Yang, Shikun, Liu, Fuyou, Zhou, Zhiguang, Zhan, Ming, Xie, Ping, Zhang, Dongshan, Li, Jun, Song, Panai, Kanwar, Yashpal S., Sun, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2014
Assuntos:
Complications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964498/
https://ncbi.nlm.nih.gov/pubmed/24353183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1412
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