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Pathogenic orphan transduction created by a non-reference LINE-1 retrotransposon
Long INterspersed Element-1 (LINE-1) retrotransposons comprise 17% of the human genome, and move by a potentially mutagenic “copy and paste” mechanism via an RNA intermediate. Recently, the retrotransposition-mediated insertion of a new transcript was described as a novel cause of genetic disease, D...
Tallennettuna:
| Päätekijät: | , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2011
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3258325/ https://ncbi.nlm.nih.gov/pubmed/22095564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.21663 |
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