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IRES-mediated translation of cellular messenger RNA operates in eIF2α- independent manner during stress

Physiological and pathophysiological stress attenuates global translation via phosphorylation of eIF2α. This in turn leads to the reprogramming of gene expression that is required for adaptive stress response. One class of cellular messenger RNAs whose translation was reported to be insensitive to e...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Thakor, Nehal, Holcik, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258125/
https://ncbi.nlm.nih.gov/pubmed/21917851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr701
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