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IRES-mediated translation of cellular messenger RNA operates in eIF2α- independent manner during stress

Physiological and pathophysiological stress attenuates global translation via phosphorylation of eIF2α. This in turn leads to the reprogramming of gene expression that is required for adaptive stress response. One class of cellular messenger RNAs whose translation was reported to be insensitive to e...

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Библиографические подробности
Главные авторы: Thakor, Nehal, Holcik, Martin
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258125/
https://ncbi.nlm.nih.gov/pubmed/21917851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr701
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