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SMRT analysis of MTOC and nuclear positioning reveals the role of EB1 and LIC1 in single-cell polarization

In several migratory cells, the microtubule-organizing center (MTOC) is repositioned between the leading edge and nucleus, creating a polarized morphology. Although our understanding of polarization has progressed as a result of various scratch-wound and cell migration studies, variations in culture...

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Detalhes bibliográficos
Main Authors: Hale, Christopher M., Chen, Wei-Chiang, Khatau, Shyam B., Daniels, Brian R., Lee, Jerry S. H., Wirtz, Denis
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258110/
https://ncbi.nlm.nih.gov/pubmed/22193958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.091231
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