A perinuclear actin cap regulates nuclear shape

Defects in nuclear morphology often correlate with the onset of disease, including cancer, progeria, cardiomyopathy, and muscular dystrophy. However, the mechanism by which a cell controls its nuclear shape is unknown. Here, we use adhesive micropatterned surfaces to control the overall shape of fib...

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Bibliographic Details
Main Authors: Khatau, Shyam B., Hale, Christopher M., Stewart-Hutchinson, P. J., Patel, Meet S., Stewart, Colin L., Searson, Peter C., Hodzic, Didier, Wirtz, Denis
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776434/
https://ncbi.nlm.nih.gov/pubmed/19850871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908686106
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