Bi-modal Dose-dependent Cardiac Response to Tetrahydrobiopterin in Pressure-overload Induced Hypertrophy and Heart Failure

The exogenous administration of tetrahydrobiopterin (BH4), an essential cofactor of nitric oxide synthase (NOS), has been shown to reduce left ventricular hypertrophy, fibrosis, and cardiac dysfunction in mice with pre-established heart disease induced by pressure-overload. In this setting, BH4 re-c...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Moens, An L., Ketner, Elizabeth A., Takimoto, Eiki, Schmidt, Tim S., O'Neill, Charles A., Wolin, Michael S., Alp, Nicholas J, Channon, Keith M., Kass, David A.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257520/
https://ncbi.nlm.nih.gov/pubmed/21645517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2011.05.017
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires