Lipid Exchange Mechanism of the Cholesteryl Ester Transfer Protein Clarified by Atomistic and Coarse-grained Simulations

Cholesteryl ester transfer protein (CETP) transports cholesteryl esters, triglycerides, and phospholipids between different lipoprotein fractions in blood plasma. The inhibition of CETP has been shown to be a sound strategy to prevent and treat the development of coronary heart disease. We employed...

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Hlavní autoři: Koivuniemi, Artturi, Vuorela, Timo, Kovanen, Petri T., Vattulainen, Ilpo, Hyvönen, Marja T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257282/
https://ncbi.nlm.nih.gov/pubmed/22253581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002299
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