How Anacetrapib Inhibits the Activity of the Cholesteryl Ester Transfer Protein? Perspective through Atomistic Simulations

Cholesteryl ester transfer protein (CETP) mediates the reciprocal transfer of neutral lipids (cholesteryl esters, triglycerides) and phospholipids between different lipoprotein fractions in human blood plasma. A novel molecular agent known as anacetrapib has been shown to inhibit CETP activity and t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS Comput Biol
Päätekijät: Äijänen, Tarja, Koivuniemi, Artturi, Javanainen, Matti, Rissanen, Sami, Rog, Tomasz, Vattulainen, Ilpo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2014
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4238956/
https://ncbi.nlm.nih.gov/pubmed/25412509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003987
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