Structure of Spheroidal HDL Particles Revealed by Combined Atomistic and Coarse-Grained Simulations

Spheroidal high-density lipoprotein (HDL) particles circulating in the blood are formed through an enzymatic process activated by apoA-I, leading to the esterification of cholesterol, which creates a hydrophobic core of cholesteryl ester molecules in the middle of the discoidal phospholipid bilayer....

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Dades bibliogràfiques
Autors principals: Catte, Andrea, Patterson, James C., Bashtovyy, Denys, Jones, Martin K., Gu, Feifei, Li, Ling, Rampioni, Aldo, Sengupta, Durba, Vuorela, Timo, Niemelä, Perttu, Karttunen, Mikko, Marrink, Siewert Jan, Vattulainen, Ilpo, Segrest, Jere P.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2008
Matèries:
Supramolecular Assemblies
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2257918/
https://ncbi.nlm.nih.gov/pubmed/18065479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.115857
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