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Role of Lipids in Spheroidal High Density Lipoproteins

We study the structure and dynamics of spherical high density lipoprotein (HDL) particles through coarse-grained multi-microsecond molecular dynamics simulations. We simulate both a lipid droplet without the apolipoprotein A-I (apoA-I) and the full HDL particle including two apoA-I molecules surroun...

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Main Authors: Vuorela, Timo, Catte, Andrea, Niemelä, Perttu S., Hall, Anette, Hyvönen, Marja T., Marrink, Siewert-Jan, Karttunen, Mikko, Vattulainen, Ilpo
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965744/
https://ncbi.nlm.nih.gov/pubmed/21060857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000964
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