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Steroidomimetic Tetrahydroisoquinolines for the Design of New Microtubule Disruptors
[Image: see text] Structure–activity relationship translation offers an expeditious means for discovery of new active series. This approach was applied to discover tetrahydroisoquinoline (THIQ)-based steroidomimetic microtubule disruptors. The two A-ring elements of a three-point steroidal pharmacop...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3256937/ https://ncbi.nlm.nih.gov/pubmed/22247790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml200232c |
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