Dissection of Wnt5a-Ror2 Signaling Leading to Matrix Metalloproteinase (MMP-13) Expression

It has been shown that constitutively active Wnt5a-Ror2 signaling in osteosarcoma cell lines plays crucial roles in induced expression of matrix metalloproteinase-13 (MMP-13), required for their invasiveness; however, it remains largely unclear about the molecular basis of MMP-13 gene induction by W...

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Autors principals: Yamagata, Kaoru, Li, Xin, Ikegaki, Shunkichi, Oneyama, Chitose, Okada, Masato, Nishita, Michiru, Minami, Yasuhiro
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256912/
https://ncbi.nlm.nih.gov/pubmed/22128168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.315127
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