Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2

BACKGROUND: Wnt signaling is mediated through 1) the beta-catenin dependent canonical pathway and, 2) the beta-catenin independent pathways. Multiple receptors, including Fzds, Lrps, Ror2 and Ryk, are involved in Wnt signaling. Ror2 is a single-span transmembrane receptor-tyrosine kinase (RTK). The...

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Main Authors: Li, Changgong, Chen, Hongyan, Hu, Lingyan, Xing, Yiming, Sasaki, Tomoyo, Villosis, Maria F, Li, John, Nishita, Michiru, Minami, Yasuhiro, Minoo, Parviz
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254434/
https://ncbi.nlm.nih.gov/pubmed/18215320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-9-11
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