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Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2
BACKGROUND: Wnt signaling is mediated through 1) the beta-catenin dependent canonical pathway and, 2) the beta-catenin independent pathways. Multiple receptors, including Fzds, Lrps, Ror2 and Ryk, are involved in Wnt signaling. Ror2 is a single-span transmembrane receptor-tyrosine kinase (RTK). The...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2254434/ https://ncbi.nlm.nih.gov/pubmed/18215320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-9-11 |
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