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Genetic interactions between Ror2 and Wnt9a, Ror1 and Wnt9a and Ror2 and Ror1: Phenotypic analysis of the limb skeleton and palate in compound mutants

Mutations in the human receptor tyrosine kinase ROR2 are associated with Robinow syndrome (RRS) and brachydactyly type B1. Amongst others, the shortened limb phenotype associated with RRS is recapitulated in Ror2(−/−) mutant mice. In contrast, Ror1(−/−) mutant mice are viable and show no limb phenot...

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Detalhes bibliográficos
Publicado no:Genes Cells
Main Authors: Weissenböck, Martina, Latham, Richard, Nishita, Michiru, Wolff, Lena Ingeborg, Henry Ho, Hsin-Yi, Minami, Yasuhiro, Hartmann, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7340625/
https://ncbi.nlm.nih.gov/pubmed/30801848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gtc.12676
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