Ror2/Frizzled Complex Mediates Wnt5a-Induced AP-1 Activation by Regulating Dishevelled Polymerization

The receptor tyrosine kinase Ror2 acts as a receptor or coreceptor for Wnt5a to mediate Wnt5a-induced activation of the Wnt/JNK pathway and inhibition of the β-catenin-dependent canonical Wnt pathway. However, little is known about how Ror2 cooperates with another receptor component(s) to mediate Wn...

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Bibliographic Details
Main Authors: Nishita, Michiru, Itsukushima, Sumiyo, Nomachi, Akira, Endo, Mitsuharu, Wang, ZhiChao, Inaba, Daisuke, Qiao, Sen, Takada, Shinji, Kikuchi, Akira, Minami, Yasuhiro
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897551/
https://ncbi.nlm.nih.gov/pubmed/20457807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00177-10
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