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Formation of Ternary Complex of Human Biliverdin Reductase-Protein Kinase Cδ-ERK2 Protein Is Essential for ERK2-mediated Activation of Elk1 Protein, Nuclear Factor-κB, and Inducible Nitric-oxidase Synthase (iNOS)
Growth factors, insulin, oxidative stress, and cytokines activate ERK1/2 by PKCδ and MEK1/2. Human biliverdin reductase (hBVR), a Ser/Thr/Tyr kinase and intracellular scaffold/bridge/anchor, is a nuclear transporter of MEK1/2-stimulated ERK1/2 (Lerner-Marmarosh, N., Miralem, T., Gibbs, P. E., and Ma...
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Hoofdauteurs: | , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
American Society for Biochemistry and Molecular Biology
2012
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3256887/ https://ncbi.nlm.nih.gov/pubmed/22065579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.279612 |
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