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BILIVERDIN REDUCTASE IS A TRANSPORTER OF HEME INTO THE NUCLEUS AND IS ESSENTIAL TO REGULATION OF HO-1 GENE EXPRESSION BY HEMATIN
Human biliverdin reductase (hBVR) is an enzyme that reduces biliverdin (the product of heme oxygenase HO-1 and HO-2 activity) to the antioxidant bilirubin. It also functions as a kinase and as a transcription factor in the MAPK signaling cascade. Fluorescence correlation spectroscopy was used to inv...
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Главные авторы: | , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
2008
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2723824/ https://ncbi.nlm.nih.gov/pubmed/18412543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20080018 |
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