BILIVERDIN REDUCTASE IS A TRANSPORTER OF HEME INTO THE NUCLEUS AND IS ESSENTIAL TO REGULATION OF HO-1 GENE EXPRESSION BY HEMATIN

Human biliverdin reductase (hBVR) is an enzyme that reduces biliverdin (the product of heme oxygenase HO-1 and HO-2 activity) to the antioxidant bilirubin. It also functions as a kinase and as a transcription factor in the MAPK signaling cascade. Fluorescence correlation spectroscopy was used to inv...

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Detalhes bibliográficos
Main Authors: Tudor, Cicerone, Lerner-Marmarosh, Nicole, Engelborghs, Yves, Gibbs, Peter E. M, Maines, Mahin D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723824/
https://ncbi.nlm.nih.gov/pubmed/18412543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20080018
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