DNA methylation profiling in Barrett's esophagus and esophageal adenocarcinoma reveals unique methylation signatures and molecular subclasses

Barrett's esophagus (BE) is a metaplastic process whereby the normal stratified, squamous esophageal epithelium is replaced by specialized intestinal epithelium. Barrett's is the only accepted precursor lesion for esophageal adenocarcinoma (EAC), a solid tumor that is rapidly increasing in...

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Autors principals: Kaz, Andrew M, Wong, Chao-Jen, Luo, Yanxin, Virgin, Jeffrey B, Washington, M Kay, Willis, Joseph E, Leidner, Rom S, Chak, Amitabh, Grady, William M
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2011
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256330/
https://ncbi.nlm.nih.gov/pubmed/22139570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.6.12.18199
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