Resistance Emergence Mechanism and Mechanism of Resistance Suppression by Tobramycin for Cefepime for Pseudomonas aeruginosa

The panoply of resistance mechanisms in Pseudomonas aeruginosa makes resistance suppression difficult. Defining optimal regimens is critical. Cefepime is a cephalosporin whose 3′ side chain provides some stability against AmpC β-lactamases. We examined the activity of cefepime against P. aeruginosa...

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Detalhes bibliográficos
Main Authors: Drusano, G. L., Bonomo, Robert A., Bahniuk, Nadzeya, Bulitta, Juergen B., VanScoy, Brian, DeFiglio, Holland, Fikes, Steven, Brown, David, Drawz, Sarah M., Kulawy, Robert, Louie, Arnold
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256024/
https://ncbi.nlm.nih.gov/pubmed/22005996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05252-11
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