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Pharmacokinetics of Tenofovir following Intravaginal and Intrarectal Administration of Tenofovir Gel to Rhesus Macaques

Tenofovir gel (1%) is being developed as a microbicide for the prevention of human immunodeficiency virus (HIV) infection and has been shown to reduce transmission to women by 39%. The gel also prevents infection in macaques when applied intravaginally or intrarectally prior to challenge with simian...

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Detalhes bibliográficos
Main Authors: Nuttall, Jeremy, Kashuba, Angela, Wang, Ruili, White, Nicole, Allen, Philip, Roberts, Jeffrey, Romano, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256015/
https://ncbi.nlm.nih.gov/pubmed/21986823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00597-11
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