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Concentrations of Dapivirine in the Rhesus Macaque and Rabbit following Once Daily Intravaginal Administration of a Gel Formulation of [(14)C]Dapivirine for 7 Days

Dapivirine is a nonnucleoside reverse transcriptase inhibitor being developed as a topical microbicide for the prevention of human immunodeficiency virus infection. The distribution of radioactivity and drug in plasma and in vaginal, cervical, and draining lymph node tissues was investigated after d...

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Hlavní autoři: Nuttall, Jeremy P., Thake, Daryl C., Lewis, Mark G., Ferkany, John W., Romano, Joseph W., Mitchnick, Mark A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258487/
https://ncbi.nlm.nih.gov/pubmed/18086845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00330-07
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