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Ligand-Bound Structures of the Dengue Virus Protease Reveal the Active Conformation

Dengue is a mosquito-borne viral hemorrhagic disease that is a major threat to human health in tropical and subtropical regions. Here we report crystal structures of a peptide covalently bound to dengue virus serotype 3 (DENV-3) protease as well as the serine-protease inhibitor aprotinin bound to th...

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Sonraí Bibleagrafaíochta
Main Authors: Noble, Christian G., Seh, Cheah Chen, Chao, Alexander T., Shi, Pei Yong
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255909/
https://ncbi.nlm.nih.gov/pubmed/22031935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06225-11
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