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Ligand-Bound Structures of the Dengue Virus Protease Reveal the Active Conformation
Dengue is a mosquito-borne viral hemorrhagic disease that is a major threat to human health in tropical and subtropical regions. Here we report crystal structures of a peptide covalently bound to dengue virus serotype 3 (DENV-3) protease as well as the serine-protease inhibitor aprotinin bound to th...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3255909/ https://ncbi.nlm.nih.gov/pubmed/22031935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06225-11 |
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