ロード中...

Conformational Flexibility of the Dengue Virus RNA-Dependent RNA Polymerase Revealed by a Complex with an Inhibitor

We report a highly reproducible method to crystallize the RNA-dependent RNA polymerase (RdRp) domain of dengue virus serotype 3 (DENV-3), allowing structure refinement to a 1.79-Å resolution and revealing amino acids not seen previously. We also present a DENV-3 polymerase/inhibitor cocrystal struct...

詳細記述

保存先:
書誌詳細
主要な著者: Noble, Christian G., Lim, Siew Pheng, Chen, Yen-Liang, Liew, Chong Wai, Yap, Lijian, Lescar, Julien, Shi, Pei-Yong
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624333/
https://ncbi.nlm.nih.gov/pubmed/23408636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00045-13
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!