Crystal Structure of the Dengue Virus RNA-Dependent RNA Polymerase Catalytic Domain at 1.85-Angstrom Resolution

Dengue fever, a neglected emerging disease for which no vaccine or antiviral agents exist at present, is caused by dengue virus, a member of the Flavivirus genus, which includes several important human pathogens, such as yellow fever and West Nile viruses. The NS5 protein from dengue virus is bifunc...

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Detalhes bibliográficos
Main Authors: Yap, Thai Leong, Xu, Ting, Chen, Yen-Liang, Malet, Helene, Egloff, Marie-Pierre, Canard, Bruno, Vasudevan, Subhash G., Lescar, Julien
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900186/
https://ncbi.nlm.nih.gov/pubmed/17301146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02283-06
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