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A multi-step strategy to obtain crystals of the dengue virus RNA-dependent RNA polymerase that diffract to high resolution

Dengue virus, a member of the Flaviviridae genus, causes dengue fever, an important emerging disease with several million infections occurring annually for which no effective therapy exists. The viral RNA-dependent RNA polymerase NS5 plays an important role in virus replication and represents an int...

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Detaylı Bibliyografya
Asıl Yazarlar: Yap, Thai Leong, Chen, Yen Liang, Xu, Ting, Wen, Daying, Vasudevan, Subhash G., Lescar, Julien
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: International Union of Crystallography 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2330120/
https://ncbi.nlm.nih.gov/pubmed/17277444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309106055084
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