טוען...
Stimulation of the Human RAD51 Nucleofilament Restricts HIV-1 Integration In Vitro and in Infected Cells
Stable HIV-1 replication requires the DNA repair of the integration locus catalyzed by cellular factors. The human RAD51 (hRAD51) protein plays a major role in homologous recombination (HR) DNA repair and was previously shown to interact with HIV-1 integrase (IN) and inhibit its activity. Here we de...
שמור ב:
Main Authors: | , , , , , , , , , , , , , , , , , , , , |
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פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
American Society for Microbiology
2012
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3255893/ https://ncbi.nlm.nih.gov/pubmed/22013044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05425-11 |
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