Latent HIV-1 Infection of Resting CD4(+) T Cells in the Humanized Rag2(−/−) γ(c)(−/−) Mouse

Persistent human immunodeficiency virus type 1 (HIV-1) infection of resting CD4(+) T cells, unaffected by antiretroviral therapy (ART), provides a long-lived reservoir of HIV infection. Therapies that target this viral reservoir are needed to eradicate HIV-1 infection. A small-animal model that reca...

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Hlavní autoři: Choudhary, Shailesh K., Archin, Nancie M., Cheema, Manzoor, Dahl, Noelle P., Garcia, J. Victor, Margolis, David M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255863/
https://ncbi.nlm.nih.gov/pubmed/22013038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05590-11
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