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Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells

Genomic instability is a common feature of cancer etiology. This provides an avenue for therapeutic intervention, since cancer cells are more susceptible than normal cells to DNA damaging agents. However, there is growing evidence that the epigenetic mechanisms that impact DNA methylation and histon...

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Bibliographic Details
Main Authors: Rajendran, Praveen, Ho, Emily, Williams, David E, Dashwood, Roderick H
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255482/
https://ncbi.nlm.nih.gov/pubmed/22247744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-3-4
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