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Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells
Genomic instability is a common feature of cancer etiology. This provides an avenue for therapeutic intervention, since cancer cells are more susceptible than normal cells to DNA damaging agents. However, there is growing evidence that the epigenetic mechanisms that impact DNA methylation and histon...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3255482/ https://ncbi.nlm.nih.gov/pubmed/22247744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-3-4 |
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