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Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells

Genomic instability is a common feature of cancer etiology. This provides an avenue for therapeutic intervention, since cancer cells are more susceptible than normal cells to DNA damaging agents. However, there is growing evidence that the epigenetic mechanisms that impact DNA methylation and histon...

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Detalhes bibliográficos
Main Authors: Rajendran, Praveen, Ho, Emily, Williams, David E, Dashwood, Roderick H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255482/
https://ncbi.nlm.nih.gov/pubmed/22247744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-3-4
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