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Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells

Genomic instability is a common feature of cancer etiology. This provides an avenue for therapeutic intervention, since cancer cells are more susceptible than normal cells to DNA damaging agents. However, there is growing evidence that the epigenetic mechanisms that impact DNA methylation and histon...

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Autori principali: Rajendran, Praveen, Ho, Emily, Williams, David E, Dashwood, Roderick H
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255482/
https://ncbi.nlm.nih.gov/pubmed/22247744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-3-4
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