FLT3-regulated antigens as targets for leukemia-reactive cytotoxic T lymphocytes

The FMS-like tyrosine kinase 3 (FLT3) is highly expressed in acute myeloid leukemia (AML). Internal tandem duplications (ITD) of the juxtamembrane domain lead to the constitutive activation of the FLT3 kinase inducing the activation of multiple genes, which may result in the expression of leukemia-a...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Brackertz, B, Conrad, H, Daniel, J, Kast, B, Krönig, H, Busch, D H, Adamski, J, Peschel, C, Bernhard, H
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2011
विषय:
Original Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255276/
https://ncbi.nlm.nih.gov/pubmed/22829124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2011.12
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