FLT3-regulated antigens as targets for leukemia-reactive cytotoxic T lymphocytes

The FMS-like tyrosine kinase 3 (FLT3) is highly expressed in acute myeloid leukemia (AML). Internal tandem duplications (ITD) of the juxtamembrane domain lead to the constitutive activation of the FLT3 kinase inducing the activation of multiple genes, which may result in the expression of leukemia-a...

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Detalhes bibliográficos
Main Authors: Brackertz, B, Conrad, H, Daniel, J, Kast, B, Krönig, H, Busch, D H, Adamski, J, Peschel, C, Bernhard, H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255276/
https://ncbi.nlm.nih.gov/pubmed/22829124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2011.12
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