FLT3-regulated antigens as targets for leukemia-reactive cytotoxic T lymphocytes

The FMS-like tyrosine kinase 3 (FLT3) is highly expressed in acute myeloid leukemia (AML). Internal tandem duplications (ITD) of the juxtamembrane domain lead to the constitutive activation of the FLT3 kinase inducing the activation of multiple genes, which may result in the expression of leukemia-a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Brackertz, B, Conrad, H, Daniel, J, Kast, B, Krönig, H, Busch, D H, Adamski, J, Peschel, C, Bernhard, H
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2011
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255276/
https://ncbi.nlm.nih.gov/pubmed/22829124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2011.12
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