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FLT3-regulated antigens as targets for leukemia-reactive cytotoxic T lymphocytes
The FMS-like tyrosine kinase 3 (FLT3) is highly expressed in acute myeloid leukemia (AML). Internal tandem duplications (ITD) of the juxtamembrane domain lead to the constitutive activation of the FLT3 kinase inducing the activation of multiple genes, which may result in the expression of leukemia-a...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3255276/ https://ncbi.nlm.nih.gov/pubmed/22829124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2011.12 |
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