MicroRNA-146a and AMD3100, two ways to control CXCR4 expression in acute myeloid leukemias

CXCR4 is a negative prognostic marker in acute myeloid leukemias (AMLs). Therefore, it is necessary to develop novel ways to inhibit CXCR4 expression in leukemia. AMD3100 is an inhibitor of CXCR4 currently used to mobilize cancer cells. CXCR4 is a target of microRNA (miR)-146a that may represent a n...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Spinello, I, Quaranta, M T, Riccioni, R, Riti, V, Pasquini, L, Boe, A, Pelosi, E, Vitale, A, Foà, R, Testa, U, Labbaye, C
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255264/
https://ncbi.nlm.nih.gov/pubmed/22829170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2011.24
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker