MicroRNA-146a and AMD3100, two ways to control CXCR4 expression in acute myeloid leukemias

CXCR4 is a negative prognostic marker in acute myeloid leukemias (AMLs). Therefore, it is necessary to develop novel ways to inhibit CXCR4 expression in leukemia. AMD3100 is an inhibitor of CXCR4 currently used to mobilize cancer cells. CXCR4 is a target of microRNA (miR)-146a that may represent a n...

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Detaylı Bibliyografya
Asıl Yazarlar: Spinello, I, Quaranta, M T, Riccioni, R, Riti, V, Pasquini, L, Boe, A, Pelosi, E, Vitale, A, Foà, R, Testa, U, Labbaye, C
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2011
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255264/
https://ncbi.nlm.nih.gov/pubmed/22829170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2011.24
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