MicroRNA-146a and AMD3100, two ways to control CXCR4 expression in acute myeloid leukemias

CXCR4 is a negative prognostic marker in acute myeloid leukemias (AMLs). Therefore, it is necessary to develop novel ways to inhibit CXCR4 expression in leukemia. AMD3100 is an inhibitor of CXCR4 currently used to mobilize cancer cells. CXCR4 is a target of microRNA (miR)-146a that may represent a n...

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Detalhes bibliográficos
Main Authors: Spinello, I, Quaranta, M T, Riccioni, R, Riti, V, Pasquini, L, Boe, A, Pelosi, E, Vitale, A, Foà, R, Testa, U, Labbaye, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255264/
https://ncbi.nlm.nih.gov/pubmed/22829170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2011.24
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