Glucocorticoid-induced cell death is mediated through reduced glucose metabolism in lymphoid leukemia cells

Malignant cells are known to have increased glucose uptake and accelerated glucose metabolism. Using liquid chromatography and mass spectrometry, we found that treatment of acute lymphoblastic leukemia (ALL) cells with the glucocorticoid (GC) dexamethasone (Dex) resulted in profound inhibition of gl...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Buentke, E, Nordström, A, Lin, H, Björklund, A-C, Laane, E, Harada, M, Lu, L, Tegnebratt, T, Stone-Elander, S, Heyman, M, Söderhäll, S, Porwit, A, Östenson, C-G, Shoshan, M, Tamm, K Pokrovskaja, Grandér, D
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
Soggetti:
Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255251/
https://ncbi.nlm.nih.gov/pubmed/22829187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2011.27
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi