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Indian Hedgehog Requires Additional Effectors besides Runx2 to Induce Osteoblast Differentiation

Indian hedgehog (Ihh) is indispensable for osteoblast differentiation during embryonic development of the endochondral skeleton. In the absence of Ihh, cells of the osteoblast lineage fail to activate the expression of Runx2, a transcription factor integral to osteoblast differentiation. However, it...

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Detalhes bibliográficos
Main Authors: Tu, Xiaolin, Joeng, Kyu Sang, Long, Fanxin
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254823/
https://ncbi.nlm.nih.gov/pubmed/22155527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.11.013
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