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Indian hedgehog signaling triggers Nkx3.2 protein degradation during chondrocyte maturation
The Indian hedgehog (Ihh) pathway plays an essential role in facilitating chondrocyte hypertrophy and bone formation during skeletal development. Nkx3.2 is initially induced in chondrocyte precursor cells, maintained in early-stage chondrocytes, and down-regulated in terminal-stage chondrocytes. Con...
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| Publicado no: | Biochem J |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4334119/ https://ncbi.nlm.nih.gov/pubmed/22507129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20112062 |
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