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Suppression of Nkx3.2 by phosphatidylinositol-3-kinase signaling regulates cartilage development by modulating chondrocyte hypertrophy

Phosphatidylinositol-3-kinase (PI3K) is a key regulator of diverse biological processes including cell proliferation, migration, survival, and differentiation. While a role of PI3K in chondrocyte differentiation has been suggested, its precise mechanisms of action are poorly understood. Here we show...

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Detalhes bibliográficos
Publicado no:Cell Signal
Main Authors: Kim, Jeong-Ah, Im, Suhjean, Cantley, Lewis C., Kim, Dae-Won
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847727/
https://ncbi.nlm.nih.gov/pubmed/26363466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2015.09.004
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