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Constitutive Activation of Gli2 Impairs Bone Formation in Postnatal Growing Mice

Indian hedgehog (Ihh) signaling is indispensable for osteoblast differentiation during endochondral bone development in the mouse embryo. We have previously shown that the Gli2 transcription activator critically mediates Ihh function in osteoblastogenesis. To explore the possibility that activation...

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Hlavní autoři: Joeng, Kyu Sang, Long, Fanxin
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3559391/
https://ncbi.nlm.nih.gov/pubmed/23383082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055134
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