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Constitutive Activation of Gli2 Impairs Bone Formation in Postnatal Growing Mice

Indian hedgehog (Ihh) signaling is indispensable for osteoblast differentiation during endochondral bone development in the mouse embryo. We have previously shown that the Gli2 transcription activator critically mediates Ihh function in osteoblastogenesis. To explore the possibility that activation...

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Bibliografiske detaljer
Main Authors: Joeng, Kyu Sang, Long, Fanxin
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3559391/
https://ncbi.nlm.nih.gov/pubmed/23383082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055134
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