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Intercalation of a new tier of transcription regulation into an ancient circuit

Changes in gene regulatory networks are a major source of evolutionary novelty1–3. Here we describe a specific type of network rewiring event, one that intercalates a new level of transcriptional control into an ancient circuit. We deduce that, over evolutionary time, the direct ancestral connection...

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Detalhes bibliográficos
Main Authors: Booth, Lauren N., Tuch, Brian B., Johnson, Alexander D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254258/
https://ncbi.nlm.nih.gov/pubmed/21164485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09560
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